Diabetic Kidney Disease (DKD) , a prevalent and severe chronic complication of diabetes, is the leading cause of chronic kid
ney disease (CKD) and end-stage renal disease (ESRD) worldwide. The pathophysiology of DKD is multifactorial, involving
dysregulated glycolipid metabolism, hemodynamic abnormalities, renin-angiotensin system (RAS) overactivation, inflam
mation, autophagy impairment, oxidative stress, mitochondrial dysfunction, and genetic/epigenetic dysregulation. Emerg
ing evidence highlights inflammation as a central driver of DKD progression
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Recent Articles
The Serum Magnesium Level of Different Etiologies of Liver Cirrhosis: A Retrospective Study
Liver cirrhosis remains a major health issue globally. Serum magnesium y is common among liver cirrhosis pa
tients, but there are very limited large-scale studies on it. Our study aimed to investigate the serum magnesium level of cir
rhotic patients and determine the distribution of serum magnesium y in t etiologies among liver cirrhosis
patients, in Hangzhou, China.
Burden of Telogen Effluvium Associated with Sjogren's Disease
Sjogren’s disease is a chronic autoimmune disease with a wide range of symptoms. A patient can first experience symptoms
from dry eyes or dry mouth to eventually progressing to more severe symptoms that can affect several organs in the body.
Hair loss can be one of the symptoms that physicians might see as less severe but can have a negative impact on a person’s
quality of life.
Adult-Onset Nesidioblastosis: A Challenge In Diagnosis and Management in Re source Limited Countries: A Case of Recurrent Hypoglycemia after Partial Pan createctomy for Nesidioblastosis
We report a 44 year old male patient with recurrent attacks of hypoglycemia (RBS 40-50 mg/dL), neuroglycopenic symp
toms, and weight loss, prompting evaluation for causes of hyperinsulinemic hypoglycemia.
