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The anti-inflammatory activity of three samples of Indomethacin (IND-S1, IND-S2, IND-F) was evaluated in two models of acute inflammation (systemic and topical) and in the model of chronic inflammation. The three sample was solubilized in Tween 80:H2 O 1:9, was tested at 20 mg/kg and was administered by intragastric route. In first evaluation, the sample IN D-S1 at 20 mg/kg showed 57.09% inhibition on carrageenan-Induced plantar edema model. The evaluation at this same dose of Indomethacin from 3 different samples (IND-S1, IND-S2, IND-F) showed a variation in the % inhibition with 34.61, 30.13 and 32.69%, respectively. On the other hand; topical anti-inflammatory activity was evaluated in the TPA mod el acute in female Balb/C mice. IND-S1 showed an ED50 = 1.31 mg/ear and at a dose of 2 mg/ear showed 56.41% of inhibi tion. IND-S1, IND-S2 and IND-F at a dose of 2 mg/ear were more active with 87.39, 90.13 and 75.87%, respectively. In the chronic model of ear edema-TPA, when the IND-S1 was administered by i.g. route at 10 mg/kg, it showed high mortality (10/10), however at dose of 8 mg/kg, IND-S1 showed a 60.63% inhibition of ear edema, but in this assay 4/10 mice head. In same assay (TPA) but the IND was administered by topic route at repeated dose of 2 and 1 mg/ear, it cuased the death of all animals and at dose of 0.5 mg/ear caused about 50% of animals deaths

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Tuberculosis is a worldwide health problem and is one of the 10 causes of death caused by a single infectious agent. It main ly affects the economically active population. Currently, there are multidrug-resistant and extended-resistance strains that are difficult to treat. In addition, several factors such as AIDS/HIV, diabetes, cancer and/or arthritis contribute to its persis tence, despite having first- and second-line drugs for its treatment. For this reason, it is necessary to contribute to find or search a new treatment alternatives and medicinal plants are an important source of bioactive compounds to be considered.

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The present study has evaluated the effects of different inclusion levels of full fat black soldier fly (BSF) (Hermetia illucens L.) larva meal on the growth performance, carcass yield, organ development and gut pH of broiler chickens. A total of nine ty Cobb 500 broiler chicken of mixed sex were reared from day 21 to day 49 and assigned to 5 dietary treatments replicated thrice with 6 birds per replicate. The BSF larva meal was included at varied levels (0, 7.5%, 15%, 22.5% and 30%) in isoni trogenous and isoenergetic diets formulated for finisher feeding phase. One chicken per pen were slaughtered at day 49 for evaluation of carcass yield, organ development and gut pH. Data was analyzed using Statistical Analysis System software (SAS, 2009) and significant means were separated using Tukey Honest Significant Difference (HSD). The results showed that the total and weekly feed intake was not affected. Live, dressed, carcass weights, total weight gained, average daily weight gain showed a significant (P<0.05) quadratic response to BSF larvae meal to a maximum of 22.5% while feed conver sion ratio (FCR) and protein efficiency ratio (PER) was optimal at 15% inclusion level. The thigh and drumstick portion posted a significant (P<0.05) positive linear and quadratic respectively. In addition, the trial diets significantly affected the weight of the liver, spleen and gizzard

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Background: Acral fibromyxoma (AFM) is a rare benign soft tissue tumor which is described as fibromatous and myxoid tumor of skin and soft tissue. Case details: A 40 year old male presented to Dematology outpatient department with swelling over the wrist for one year duration.The swelling was associated with mild pain and it gradually increased in size to reach the present size. Cutaneous examination revealed a 2x2cm mobile,cystic to firm, non-tender swelling over dorsum of right wrist. Based on its location and clinical feature,it was provisionally diagnosed to be ganglion cyst and excision biopsy was done. Histology showed stellate shaped cells in myxoid background with round to oval nuclei having small inconspicious nucleolus

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Necrotizing granulomatous inflammation in swellings which are clinically diagnosed as ganglion cyst is a rare entity due to the non-specific clinical presentation, insidious course, and large number of mimickers at this the particular site.Our patient is a 47 year/female who presented with a swelling over wrist for one year. On examination it was found to be firm, lobulated, mobile swelling, non-tender. USG showed cystic soft tissue swelling with a impression of ganglion cyst. Grossly the swelling was measuring 4x4 cm which was gradually progressive, increasing in size. This case report highlights the rare site of a granulomatous fungal inflammation clinically presenting as a multilocular ganglion cyst

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A nodular subcutaneous swelling at elbow in an elderly patient should raise suspicion of infection or malignancy. A 63 year male patient presented with painful swelling in right elbow which was present for two years. It was insidious in onset and gradually increased to the present size. Clinical examination revealed a 6x5x5cm soft swelling, compressible, non-reducible, tender and overlying skin was pinch able. The uric acid level was 8.3mg/dl which was within normal limit. Patient complained that pain worsened on intake of alcohol and used to subside upon medication. The main clinical differential diagnosis were bursitis and gouty arthritis. On histopathological examination it revealed Gouty arthritis after ruling out granulomatous inflammation, foreign body giant cell reaction.

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Introduction: Adult patients undergoing orthodontic treatment usually show signs of unbalanced occlusion, which can lead to serious health problems. Any imbalance in the body requires increased energy input for adaptation. Over time, this can lead to maladaptation and the formation of pathology throughout the body. For this reason, the examination of such patients requires special attention and the treatment demands unconventional approach

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To meet people's yearning for a better life and the needs of agricultural production services, we must use soil water resources sustainably and carry out Agriculture high-quality development. So, we must estimate and take the suitable initial planting density to sow or plant to ensure Plant conservation density in the critical period of plant resources relation regulation reach the vegetation carry capacity to get the maximum yield and beneficial result. However, there are few reports on the estimation method of suitable initial planting density. In this pater, we put forward a method to estimating the suitable initial planting density, and take the perennial plant, caragana in the semiarid loess hilly region and one year plant, pepper in Xunhua, China as an example to determine. The results showing that the estimation method of suitable initial planting density is different for perennial plant caragana and one year plant, we can estimate the suitable initial planting density according to the soil dryness degree of control in the first year in the shrubland of semiarid region. As for a year plant pepper, we can estimate suitable initial planting density according to the area occupied by standard plant with maximum yield and beneficial result in the end of growth season.

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Spatial analysis is an essential component of Geographic Information Systems (GIS) and is widely used for various purposes. One of its primary applications is to assess the suitability of a location for specific systems or to make accurate weather predictions for a particular geographic area. By utilizing spatial analysis, users can effectively model problems and find comprehensive solutions that incorporate geographical attributes

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Background: Due to recent advancements in technology, workplace settings are becoming more inhabitant leading to a growing rate of sedentary behaviour during occupational duties. Sedentary behaviour is associated with increased cardiometabolic risks and poor health outcomes

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Flood vulnerability modeling has become essential due to the impact of climate change on the environment. The Ogbese area of Nigeria frequently experiences significant flooding, primarily caused by torrential rainfall that leads to the overflow of local rivers. This study aims to model and map flood vulnerability in the Ogbese Catchment area in Ayede-Ogbese. Advanced analytical techniques, including Remote Sensing (RS), Hydraulic Engineering Center-River Analysis Software (HEC-RAS), and Geographical Information System (GIS) software (ArcGIS 10.7), were utilized for flood modeling and mapping in the study area. The data used in this research includes a topographic map of Ondo State for delineating the study area, Operational Landsat Imageries (OLI) for extracting land use and land cover (LULC), hydrological data (river discharge) for flood frequency analysis, and Advanced Land Observing Satellite (ALOS) Digital Elevation Map (DEM) for geometric data extraction and generating a Triangulated Irregular Network (TIN) dataset

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Sympathy- seeking behavior or “sadfishing”, the act of exaggerating emotional distress on social media to gain “attention, satisfaction and support system. In recent years, this kind of act have rise of social media platform. This has become online interactions and potential psychology and social effects of behavior have become topics of interest. This study was prevalence and implication was done among the individuals through Questionnaire. Which was surveyed among college student. The Questionnaire covered key aspects of the participants in three dimension like attention, satisfaction and support system. The study provides valuable insights into the emerging phenomenon of sadfishing, though it also presented limitations such as potential self-report biases and lack of contextual depth. Future research could benefit from integrating observational methods and experimental designs to build a more nuanced understanding of sadfishing and its implications in the digital age

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Early copper deficiency detection is important for sheep, a sensitive animal to copper (Cu) nutrition. Diagnosis through blood copper, ceruloplasmin, and superoxide dismutase 1 (SOD1) enzymes is not ideal due to the multifactorial control of these parameters. The copper chaperone for superoxide dismutase (CCS) protein is reported to be a specific biomarker for Cu deficiency in cattle and mice but not in sheep

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Data of patients still alive 10 years after initial treatment for multiple myeloma (MM) were collected by 13 Italian hematological centers from January 2020 to December 2022. Routine work-up at diagnosis and type of treatment of 201 patients were analyzed from December 2023 to March 2024

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Background: Calprotectin (CPL) is a marker of neutrophil-induced inflammation. Objective: Assess whether salivary CPL could be a useful marker of chronic inflammation. Methods: All relevant data were collected about patients who consulted from 2024 October 20th to December 20th and who had a previous medical history of periodontitis (PO).Patients were classified according to the level of salivary CPL. The CPL threshold for active PO and/or Fusobacterium nucleatum + Porphyromonas gingivalis (Fn+Pg) on dental collets was determined. Patients with PO remission, without Fn+Pg on dental collets and below the identified threshold were attributed to group A. Other patients were attributed to group B. Both groups were compared

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With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.

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The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.

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Self-organized anodic porous alumina films with hexagonal pore lattice have attracted a considerable attention for biological arrays and confinement of various organic probes dyes in solutions. A molecular structure with axial symmetry in bis-heterocyclic indole chains and conjugate system, such as cyanine fluorophore Cy3 dye, was investigated here with respect to its fluorescence when loaded in the anodic alumina pores.

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Two basic reactions occur during the anodizing of aluminum: 1) the aluminum is consumed and 2) an oxide grows. By accepting this statement as true, the anodizing process can be viewed as a corrosion process, and anodizing can be modeled using the Tafel Equation. Anodizing process parameters of electrolyte chemistry and concentration, temperature, aluminum substrate resistance and current density are presented as they relate to the Tafel Equation and how they impact the anodic aluminum oxide structure and properties. Understanding this relationship is consequent in making anodizing an engineering process, one that enables tuning the structure such that it yields distinct characteristics to fulfill design and application requirements.

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Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.

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The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.

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Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.

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The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.

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The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.

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Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.

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We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.

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The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.

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Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.

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Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.

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In this paper, we report on the synthesis of BaTiO3 nanowires via the anodic aluminum oxide template method. To fill in the precursors of BaTiO3 into anodic aluminum oxide templates, the vacuum and drop loading method developed in our previous study was used. Ba(CH3COO)2 (barium acetate) and C12H28O4Ti (tetraisopropyl orthotitanate) were used as Ba and Ti sources, respectively. Anodic aluminum oxide membranes with the through-hole diameter of ~200 nm were used as the template for BaTiO3 nanowires.

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