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Figure 1: Flow chart of retrospettive study design |
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Figure 2: Graphical abstract |
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Figure 3: Sterol regulatory element-binding transcription factor 1 (SREBF1) gene expression in HEPG2 cells treated with 3 M of resveratrol and co-treatment with 500nM lipoic acid at 37 degrees celcius for 24h. |
Patient demographic data |
Control |
RSV + ALA |
p |
Age |
32.8 ± 5.1 |
31.9 ± 4.7 |
0.41 |
Pregestational BMI |
26.6 ± 3.4 |
27.5 ± 3.6 |
0.25 |
Rate of nulliparous |
23/40 (57.5%) |
15/40 (37.5%) |
0.08 |
Mode of delivery |
|||
Cesarean section |
11/40 (27.5%) |
9/40 (22.5%) |
0.61 |
Vaginal delivery |
29/40 (72.5%) |
31/40 (77.5%) |
0.61 |
Outcome |
Control |
RSV + ALA |
p |
Insulin require |
15/40 (37.5%) |
6/40 (15.0%) |
0.02 |
Daily insulin requirement (IU) |
14 ± 3 |
11 ± 2 |
<0.0001 |
Fasting glucose level (mg/dL) |
93 ± 5 |
87 ± 4 |
<0.0001 |
Postprandial glucose level (mg/dL) |
142 ± 10 |
139 ± 7 |
0.12 |
Large for gestational age |
5/40 (12.5%) |
4/40 (10.0%) |
0.74 |