Journal of Gynecology Research

Dr. Patricia A. Kruk is currently working as a Professor, Obstetrics and Gynecology, USF Morsani College of Medicine. She holds a membership in various international societies. She is reviewer and Editorial board member in various international journals. She received Robert J. Grasso Award, University of South Florida for the year 2012-13. She has number of publications on her name.

Dr. Patricia A. Kruk research interests includes, Ovarian epithelial cancer is the leading cause of gynecologic cancer death in women in the US, the fourth leading cause of cancer death among women and is associated with a 1.7% lifetime risk.  It is estimated that 23,100 new cases are diagnosed in the U.S. annually and that 14,000 women die annually from this disease. Her research focuses on the molecular changes responsible for early stages contributing to ovarian cancer in a bench-to-bedside manner using human tissue culture and clinical specimens. Current studies include: understanding the molecular mechanisms by which germline mutations in an ovarian cancer susceptibility gene, BRCA1, alter patients’ response to chemotherapy and promote malignant transformation; delineating the molecular mechanisms that regulate telomerase, an enzyme that confers cellular immortalization and an important, early step in malignant transformation and; developing a potential urinary clinical diagnostic/prognostic test for ovarian cancer. Taken together, her lab remains devoted and committed to impacting the welfare of women.